A female kangaroo and joey shot by an arrow at Lake Innes Drive on Sunday have been euthanased.
The wildlife rescue service FAWNA described the event as an 'extreme act of cruelty'.
The incident was reported to FAWNA and the police on Sunday.
President Meredith Ryan said a joey was retrieved from the pouch but it also had been injured by the arrow.
"It was suffering from a broken metatarsal and the injury resulted in necrotic tissue rendering it unhealable and FAWNA would not be able to rehabilitate the joey," she said.
"A veterinary inspection by Dr. Paws Vet confirmed that the joey also needed to be euthanased.
"This extreme act of cruelty has shocked all people involved in getting help for these native animals so callously maimed by one or more dysfunctional human beings".
The incident has been reported to Port Macquarie Police and RSPCA and the volunteer wildlife rescue group hopes a thorough investigation will identify the perpetrators and bring some justice for these innocent animals.
Meanwhile Ms Ryan has urged motorists and the public to report all incidents involving wildlife.
Her calls follows FAWNA decision to euthanase a red-necked wallaby on Bellangry Road, near Peadsville on Monday.
While travelling to that incident, FAWNA staff noticed a further three unreported injured wildlife.
"We were called to an incident involving a female sub adult about 6Kg," she said.
"However, our volunteers also noticed a further three injured male red-necked wallaby adults.
"FAWNA urges motorists to take more care on the roads and to be aware of what is in their peripheral vision.
"Drivers should slow down in known wildlife roadkill spots."
Ms Ryan said if a drivers does hit something, they should check the pouch and, if possible, bring the animal to town.